Reply to “Immune response of condyloma acuminatum after 5-aminolevulinicacid-photodynamic therapy treatment”

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Giant Condyloma Acuminatum of Vulva Frustrating Treatment Challenge

Giant condylomata are not usually seen nowadays in developed nations, but such cases are still seen in the under-resourced countries. Condylomata acuminata are commonly transmitted through sexual intercourse. Generally diagnosed based on their appearance. Giant condyloma acuminata also named Buschke- Löwenstein tumour (BLT) is a slow growing cauliflower-like tumor, locally aggressive and destru...

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BuschkeeLöwenstein tumor (giant condyloma acuminatum) successfully treated by topical photodynamic therapy: a case report

Giant condyloma acuminatum (BuschkeeLöwenstein tumor) is a rare sexually transmitted disease caused by human papilloma virus infection in the anogenital area. It is characterized by rapid growth, large size, local destruction, lack of spontaneous resolution, poor response to conservative therapy (e.g., cryotherapy), and a high recurrence rate. Treatment of such tumors remains challenging. We re...

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Condyloma acuminatum: its histopathological pattern.

Condyloma acuminatum is one of the clinical manifestations of papillomavirus infection. The classical histopathological features are already known and do not constitute a diagnostic problem. Clinically, it has been classified into growth or proliferative, full-expression, and regressive or persistent phases, with the histopathological aspects of these distinct phases being well documented in eq...

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Stimulation of dendritic cells enhances immune response after photodynamic therapy

Photodynamic therapy (PDT) involves the administration of photosensitizers followed by illumination of the primary tumor with red light producing reactive oxygen species that cause vascular shutdown and tumor cell necrosis and apoptosis. Anti-tumor immunity is stimulated after PDT due to the acute inflammatory response, priming of the immune system to recognize tumor-associated antigens (TAA). ...

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Giant condyloma acuminatum–malignant transformation

Giant condyloma acuminata are associated with malignant transformation in up to 50% of cases, high recurrence rate, and poor prognosis. Treatment strategies have included wide local excision, abdominopelvic resection, and addition of radiotherapy and adjuvant and/or neoadjuvant systemic chemotherapy.

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ژورنال

عنوان ژورنال: Journal of the Chinese Medical Association

سال: 2019

ISSN: 1726-4901

DOI: 10.1097/jcma.0000000000000141